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Depression in Later Life by Robert Baldwin

By Robert Baldwin

Melancholy impacts among 10-15% of older humans, making it the main often encountered psychological well-being situation in later existence. regardless of this, the situation is definitely overlooked in medical perform or no longer correctly treated.

Part of the Oxford Psychiatry Library, this concise pocketbook presents an available account of what melancholy in older humans is like, why it can be crucial, and what remedies aid. The textual content highlights which parts of melancholy are of unique relevance to later existence, tips to diagnose melancholy in an older individual, the overlap with dementia and diverse different actual health problems, and demanding pharmacological issues.

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Corticotropin-releasing hormone mRNA levels in the paraventricular nucleus of patients with Alzheimer’s disease and depression. Archives of General Psychiatry, 152, 1372–6. Rovner BW, Casten RJ, and Hegel MT (2007). Preventing depression in age-related macular degeneration. Archives of General Psychiatry, 64(8), 886–92. Aetiology CHAPTER 4 Tarangano FE, Bagnatti P, and Allegri RF (2005). A double-blind, randomized clinical trial to assess the augmentation with nimodipine of antidepressant therapy in the treatment of vascular depression.

International Journal of Geriatric Psychiatry, 23, 993–1000. Thompson C, Syddall H, Rodin I, Osmond C, and Barker DJP (2001). Birth weight and the risk of depressive disorder in late life. The British Journal of Psychiatry, 179, 450–5. Unützer J, Katon W, Sullivan M, and Miranda J (1999). Treating depressed older adults in primary care: narrowing the gap between efficacy and effectiveness. The Millbank Quarterly; 77, 225–56. Van den Berg MD, Oldehinkel AJ, Bouhuys AL, Brilman EI, Beekman ATF, and Ormel J (2001).

It affects 20%–25% of survivors in the first 6 months after stroke (Paranthaman and Baldwin 2006). Although it declines in frequency and severity over the first year, at 12 months about 10%–15% of survivors remain affected, with some having persistent severe problems. Depressed mood and emotionalism can occur together, but most people with emotionalism are not depressed. It can occur following a single cortical stroke or bilateral subcortical strokes. There may be a link to serotonergic mechanisms as lesions have been noted more commonly in the raphae nuclei, which is an area rich in serotonergic neurons (Paranthaman and Baldwin 2006).

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