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Dermatokosmetik by Professor Dr. med. Martina Kerscher (auth.)

By Professor Dr. med. Martina Kerscher (auth.)

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Extra resources for Dermatokosmetik

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Chung JH, Seo JY, Choi HR, Lee MK, Youn CS, Rhie G, Cho KH, Kim KH, Park KC, Eun HC (2001) Modulation of skin collagen metabolism in aged and photoaged human skin in vivo. J Invest Dermatol117:1218-1224 17. Cooper KD, Oberhelman L, Rarnilton TA, Baadsgaard 0, Terhune M, LeVee G, Anderson T, Koren H (1992) UV exposure reduces immunization rates and promotes tolerance to epicutaneous antigens in humans: relationship to dose, CD1a-DR+ epidermal macrophage induction, and Langerhans cell depletion. Proc Natl Acad Sei USA 89:8497-8501 18.

UVA stellt mit mehr als 95% den Hauptanteil des UV-Lichtes der Sonne dar. Es ist 800-1 OOOfach weniger erythematogen als UVB (kein UVA-Erythem bei Dosen bis zu 100 J/cm 2 ). Aufgrund seines hohen prozentualen Anteils am natürlichen Sonnenlicht kann UVA aber für bis zu 15% der erythematogenen Reaktion zur Mittagszeit verantwortlich sein [26]. UVA bewirkt eine (Früh- und Spät-) Pigmentierung der Haut. So wird in der Fotodiagnostik bei Ablesung einer UVALichttreppe neben der MTD (Minimal Tanning Dose = niedrigste UVA-Dosis, die nach 24 h eine sichtbare Pigmentierung auslöst) auch die IPD (Immediate Pigment Darkening = niedrigste UVA-Dosis, die unmittelbar nach Bestrahlung eine sichtbare, grau-bräunliche Pigmentierung induziert) bestimmt.

Varani J, Spearman D, Perone P, Fligiel SE, Datta SC, Wang ZQ, Shao Y, Kang S, Fisher GJ, Voorhees JJ (2001) Inhibition of type I procollagen synthesis by damaged collagen in photoaged skin and by collagenase-degraded collagen in vitro. Am J Pathol 158:931-942 33. Watson RE, Craven NM, Kang S, Jones CJ, Kielty CM, Griffiths CE (2001) A short-term screening protocol, using fibrillin-1 as a reporter molecule, for photoaging repair agents. J Invest Dermatol 116:672-678 34. Wertz PW, Swartzendruber DC, Kitko DJ, Madison KC, Downing D (1989) The role of the corneocyte lipid envelopes in cohesion of the stratum corneum.

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